![]() To evaluate the neurobiological basis of traumatic dissociation, this study will recruit patients with PTSD or DID and recruit matched controls to identify neurobiological correlates of traumatic dissociation. The investigators also believe that a genetic approach holds promise as another converging line of inquiry into our understanding of traumatic dissociation. Given the presumed region-to-region neural interplay implicit within this model, the investigators believe the use of intrinsic functional connectivity MRI (fcMRI) represents a valuable next line of investigation into the neurobiology of traumatic dissociation. Preliminary evidence from functional magnetic resonance imaging-based analysis (fMRI) of neural activation during dissociative symptom provocation in patients with PTSD or DID has implicated specific key structures involved in the generation of dissociative symptoms. This study aims to evaluate the neurobiological basis of traumatic dissociation in a cross-diagnostic sample of women who have histories of childhood abuse and neglect.ĭissociative symptoms are commonly associated with exposure to traumatic stress. Principal investigator: Kyle Williams, MD PhD Title: Evaluating the Neurobiological Basis of Traumatic Dissociation in Women With Histories of Abuse and Neglect The scientists suggest that this protein might be a focus for further research into potential treatments. The researchers also identified a particular protein that seemed to generate the triggering brain activity. Experiments on mice and an epileptic patient who experienced dissociative episodes appeared to identify a pattern of electrical brain activity associated with the episodes. Researchers hope that identifying a neurological mechanism underlying the experience of dissociation may lead to more effective treatment of all these disorders.Ī recent study at Stanford University attempted to look for patterns of brain activity that may be associated with dissociative episodes. Dissociation is at the heart of DID and other dissociative disorders, and it plays a role in some other neurological conditions such as epilepsy. Scientists don’t precisely understand what is happening in the brains of people who experience dissociation, a feeling of being disconnected from a sense of self. PLEASE CONSULT A PHYSICIAN FOR MORE INFORMATION.ĭissociative Identity Disorder Brain Science Symptoms have a significant negative impact on everyday functioning.Symptoms can’t be explained by substance use, medical issues, or normal imaginative play in children.No cultural or religious explanation for the symptoms.Presence of two or more distinct personalities or identities.The disorder’s diagnostic criteria include: Psychiatric exams to compare the patient’s symptoms to the diagnostic criteria for DID.Physical exams and medical histories to look for underlying neurological or physical problems that may be triggering the symptoms.Instead, to diagnose the disorder, medical doctors and mental health professionals will work together on several diagnostic steps to rule out other possible causes for the symptoms and confirm a DID diagnosis. There are no tests or exams that can definitively identify DID. How Is Dissociative Identity Disorder Diagnosed?
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